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Production Research & Development

Animal Cell Culture Technology for the Production of Biologics

Course Start: April 1, 2027

(CB203V) Protein drugs or biopharmaceuticals are taking an increasing part among therapeutic drugs world-wide. Furthermore, a large majority of these are produced from animal cell cultivation based processes. This course gives the fundaments of animal cell cultivation for the production of protein drugs in the pharmaceutical industry, and how these processes are developed, for which practical application is given through simulation software.

Course info

  • Type: University Course
  • Organization: KTH
  • Start Date: April 1, 2027
  • Language: English
  • Place: Stockholm
Course Information

Photo: KTH

 

Course contents

The course teaches theory and methodology in the field of cell technology applied to animal cells.

Theoretical concepts included

  • basic techniques for animal cell culture in shake flasks and small-scale bioreactors
  • description and use of stable expression systems (cell lines)
  • overview of animal cell metabolism during cultivation, and its application in process design
  • aspects concerning commercial production such as patient safety
  • application of knowledge from the course to develop and design culture processes, including aspects of scale-up for industrial application

The student also receives practical training with the support of computer simulation in

  • developing a culture process for industrial application

Intended learning outcomes

After passing the course, the student should be able to:

  • demonstrate knowledge of key theoretical concepts and basic methodology regarding the cultivation process of animal cells
  • demonstrate the ability to use acquired knowledge to design, motivate and present strategies for animal cell culture process in order to manufacture a therapeutic biologics

Course code: CB203V
Course format: University Master’s Course
Course duration: 4 ECTS